The San Francisco 49ers and the Dallas Cowboys are set to meet in a highly anticipated NFL Week 10 matchup on Sunday, November 15, 2026. The game is scheduled to begin at 4:25 p.m. ET at AT&T Stadium in Arlington, Texas. This contest features two of the league's most potent offenses, with the 49ers holding a 7-1 record and the Cowboys sitting at 4-5.
Current market odds on the prediction platform Kalshi indicate that the 49ers are the clear favorites to take the win. A share for a San Francisco victory is trading at $0.67, which reflects a 67% probability. In contrast, a Cowboys victory is trading at $0.34, suggesting a 34% chance of success for Dallas. New users can access these markets by using the promo code CBSSPORTS55, which offers a $55 bonus after making trades totaling $25 or more.
The 49ers enter this game with strong credentials, boasting the best record in the NFC and tying the Buffalo Bills for the best overall record in the NFL. San Francisco fields a top-five scoring offense and maintains a sixth-ranked scoring defense. Quarterback Brock Purdy is considered a contender for MVP honors, and the team is expected to receive offensive reinforcements in the coming weeks. The 49ers are coming off a decisive victory over the Las Vegas Raiders following their Week 8 bye.
The Cowboys, meanwhile, are navigating a season characterized by offensive strength and defensive struggles. While their passing attack remains among the best in the league, the defense ranks in the bottom 10 in both points and yards allowed. Dallas currently sits in second place in the NFC East behind the New York Giants, who hold a 5-2-1 record. The Cowboys secured a narrow win at Indianapolis in the previous week, driven by strong performances from Dak Prescott and CeeDee Lamb.
In terms of the point spread, the 49ers are favored to win by more than 3.5 points. The 'Yes' side for this outcome is trading at $0.52, while the 'No' side is at $0.49. San Francisco's defense allows just 19.5 points per game, making them difficult to overcome. However, four of Dallas' five losses this season have been by just one score, indicating that the Cowboys often stay close in games. The SportsLine Projection Model, which simulates games 10,000 times, shows the Cowboys winning 42% of the time and covering the spread in the majority of simulations.
The total points line for the game is set at 55.5. Both the 'Over' and 'Under' sides are trading at $0.52 and $0.49, respectively. The two teams combined average 56.7 points per game, highlighting the high-scoring nature of their offenses. While San Francisco has a defensive edge, they have allowed 29 points to both Atlanta and Seattle and 30 points to Arizona earlier in the season. The projection model predicts that more than 55.5 points will be scored in 64% of simulations.
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Fans and traders can follow the odds and place their bets ahead of the kickoff. The game promises to be a competitive affair given the high level of play from both quarterbacks and the playmakers on each roster. As the teams prepare for the weekend, the market data suggests a slight edge for San Francisco, but the Cowboys' ability to keep games close makes them a dangerous opponent.
