The early lines for NFL Week 10 are out, but bettors have an extra variable this time: the trade deadline. Deals struck before Tuesday at 4:01 p.m. ET, two days before Washington visits the New York Giants on Thursday night, could move numbers across the slate. Indianapolis is a 2.5-point home favorite against Miami, but what if the Colts trade running back Jonathan Taylor? A Chiefs move for a wide receiver would likely shift their line at Atlanta, where Kansas City is a 3.5-point road favorite. All lines are via DraftKings. Chicago, Denver, Philadelphia and Tampa Bay are on the bye.

The Giants are a slim 1.5-point favorite in Thursday's NFC East meeting with Washington. The teams tied earlier this season, but New York had Jameis Winston under center then and now turns to J.J. McCarthy. New York is 6-2 against the spread, including 3-1 at home, while Washington is 2-1 ATS on the road.

Sunday's international game in Munich has already moved. New England opened as a 1.5-point favorite against Detroit, but a blowout home loss to Green Bay flipped the number, and the Lions now lay 2.5. Neither club has been kind to bettors: Detroit is 3-4-1 ATS and New England 3-5-1, though the over is 11-6 between them.

Jacksonville opened as a 10-point favorite at Tennessee before ticking down to 9.5. Liam Coen's Jaguars are 5-3 ATS, while the Titans are 1-3 ATS at home. Carolina is a 1.5-point road favorite at New Orleans. The Panthers have lost three straight, and the Saints are 0-4 ATS at the Superdome.

Houston, fresh off a bye and a win over the Chargers in which C.J. Stroud threw five touchdowns, is a 4.5-point road favorite at Cleveland despite a 3-5 record, though the Browns are 3-0 ATS at home. Buffalo's line at the Jets has moved from 7.5 to 8.5 and could shift again after the Bills play Minnesota on Monday night. The Jets have lost four straight but catch Buffalo on a short week.

The Miami at Indianapolis line may be the week's most volatile. Taylor, Daniel Jones and Josh Downs have all surfaced as possible Colts trade candidates, though the latest reports say Jones will stay. Miami is 2-2 ATS on the road and Indianapolis is 2-2 ATS at home.

Green Bay opened as a 3-point favorite against Minnesota after Jordan Love totaled four touchdowns in a rout at New England. The Vikings won the Week 1 meeting 39-22, with Love committing two turnovers. Kansas City has moved from a 3-point to a 3.5-point favorite at Atlanta, which returns from a game in Madrid. The Chiefs are just 1-3 ATS on the road, but Patrick Mahomes avoided serious injury when an MRI on his elbow showed no damage.

Seattle is a 3-point road favorite at Las Vegas, another game with deadline angles. If the Raiders trade Kirk Cousins, considered unlikely, Fernando Mendoza would make his first career start. The defending champion Seahawks have their own quarterback concerns: Sam Darnold missed Week 9 with a quad injury and is not a lock to return, and backup Drew Lock has an oblique injury. The Rams have dipped from 8.5 to 7-point favorites at Arizona as Puka Nacua nurses a knee injury and Davante Adams remains out. The Cardinals, possible sellers, are 0-3 ATS at home.

San Francisco is a 4.5-point road favorite at Dallas after both teams won in Week 9; the Cowboys have yet to be a home underdog this season. Cincinnati, powered by Joe Burrow's MVP-level play, is a 3.5-point favorite against Pittsburgh but returns from Madrid to face a Steelers team coming off a bye. In Monday's finale, Baltimore, likely starting newly acquired Jacoby Brissett, is a 4.5-point favorite against the winless Chargers, who are 0-8 straight up and 0-7-1 ATS, while the Ravens seek their first home cover after an 0-4 ATS start.