The Pistons, missing Jalen Duren, face the Knicks in a key matchup on Tuesday. The Pistons, without injured All-Star center Jalen Duren, are visiting the surprisingly winless defending champion New York Knicks. The Knicks are in panic mode, having lost as many games in five days this season as they did during their historic playoff run last spring. The game is set for an 8 p.m. ET start time in the first of four regular-season meetings between Eastern Conference contenders.

The Pistons are favored by 4.5 points, and the total is set at 219.5. Fans interested in can keep up with NBA news and follow our experts to be prepared before wagering at any of the top . Bet on NBA props and more at DraftKings and get $200 in bonus bets plus three free months of NBA League Pass.

The Pistons' Jalen Duren, who signed a $200 million contract extension on the eve of the season after some pretty contentious negotiations with the Pistons, will miss at least two weeks with a right hamstring strain suffered in Friday's win over Miami. The Pistons dominated the boards, 54-37, but I don't think that's going to be the case tonight or often while Duren is sitting.

The Knicks could be in a good spot here, then, if that trio is all out for the Pistons. They could use a break, as they're caught up in a bit of an NBA championship hangover at 0-3 following Sunday's 111-102 home loss to an Orlando team missing star Paolo Banchero. Bet on NBA futures with the Caesars Sportsbook promo code CBSSPORTSBR250 and double your winnings on 10 bets.

The Knicks might be defending NBA champions, but maybe they wouldn't have been had they faced the Pistons in the 2026 postseason as Detroit dominated the regular-season series in winning all three by double digits. Cade Cunningham averaged 27.3 points and 11.0 assists in the three, while Duren missed them all due to injury or suspension.