The Week 7 NFL schedule wraps up on Monday night with an NFC East matchup, as the Dallas Cowboys travel to face the Philadelphia Eagles at 8:15 p.m. ET on 'Monday Night Football.' Dallas is a 4.5-point favorite, and the over/under is set at 43.5.

The injury report is the dominant storyline. Eagles quarterback Jalen Hurts remains out with blood clots, and receiver DeVonta Smith has been ruled out with a hamstring injury. Running back Saquon Barkley, who is also dealing with a hamstring problem, is officially listed as questionable but is expected to play. Two of his backups are already on injured reserve, which leaves the Philadelphia offense with limited depth.

Those absences create difficult decisions for daily Fantasy football players building lineups for the single-game slate on sites such as FanDuel and DraftKings. SportsLine analyst Mike McClure, a professional DFS player with more than $2 million in career winnings, has released his picks for the game using a model that simulates every snap and accounts for matchups, trends and injuries.

One of McClure's choices is Eagles tight end Dallas Goedert. Goedert leads all Philadelphia pass catchers with a receiving yards over/under of 49.5. With Smith and fellow receiver Dontayvion Wicks both ruled out, he is positioned to be the top target for quarterback Tanner McKee. Goedert is coming off back-to-back games with six catches. If the Eagles trail as underdogs, he could see added opportunity.

On the Dallas side, McClure is building around wide receiver CeeDee Lamb. Lamb averages 11.5 targets per game, second in the NFL behind only Puka Nacua. He has been targeted at least 18 times in two of the past three games, and he has put up at least 112 receiving yards in three games this season.

The matchup also favors Lamb. The Eagles have allowed the third-most Fantasy points to opposing receivers this year, which makes him a high-upside option on a slate with only one game.

McClure says he is also targeting an undervalued player he believes could produce big numbers on Monday night, but that name and the rest of his lineup advice are available only to SportsLine members.